Citation:
Pankaj Baral, Kimbria Mills, Felipe A Pinho-Ribeiro, and Isaac M Chiu. 2016. “Pain and Itch: Beneficial or Harmful to Antimicrobial Defense?” Cell Host Microbe, 19, 6, Pp. 755-9. Copy at http://www.tinyurl.com/y2fmde6x
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Abstract:
Pain and itch are unpleasant sensations accompanying many microbial infections. Recent studies demonstrate that pain- and itch-mediating somatosensory neurons are able to directly detect pathogens, triggering neuronal activation and subsequent regulation of immune responses. We discuss whether pain and/or itch during infection is beneficial or harmful to host antimicrobial defense.See also: Review Papers