A neuropeptide regulates immunity across species

Publication information:

Liwen Deng and Isaac Chiu. 2022. “A Neuropeptide Regulates Immunity across Species”. Neuron, 110, 8, Pp. 1275-77. doi:10.1016/j.neuron.2022.03.036

Abstract

Communication between the nervous system and immune system is important for regulating immunity in health and disease. Yu et al. (2022) show that neuropeptide Y and its homolog NPF serve as a "language" to facilitate crosstalk between these two systems across species, enabling neurons to downregulate harmful immune responses.