# Publications ### [Google Scholar Citations](https://scholar.google.com/citations?user=KxIygDoAAAAJ&hl=en&oi=ao) [PubMed Citations](https://pubmed.ncbi.nlm.nih.gov/?term=isaac+chiu&sort=date) Sort & Filters close ## Filters Publications expand\_more - Primary Research Papers (55) - Review Papers (28) - Editorial Papers (1) - Comment (3) Year of Publication expand\_more 2025 (9) 2024 (14) 2023 (10) 2022 (10) 2021 (6) 2020 (8) 2019 (6) 2018 (6) 2017 (6) 2016 (2) 2015 (3) 2014 (1) 2013 (2) 2012 (1) 2010 (1) 2009 (1) 2008 (1) 2007 (1) 2006 (3) 2004 (2) 1999 (2) 1997 (1) Publications by author expand\_more Alexander Horswill (2) Amanda Jacobson (3) Angela Kennedy-Curran (2) Antonia Wallrapp (6) Aviv Regev (3) Bela Kosaras (2) Benoit Michot (2) Brian Wainger (2) Brian Wainger (2) Bruce Bean (2) Bruce Levy (3) Caroline Perner (2) Caroline Sokol (2) ChieYu Lin (2) Christian Von Hehn (2) Christophe Benoist (4) Clifford Woolf (8) Daniela Vega-Mendoza (2) Daniel Davis (3) Daping Yang (8) David Artis (2) David Roberson (2) David Weitz (1) Deepshika Ramanan (2) Dennis Kasper (3) Diane Mathis (4) Dongxu Liu (2) Douglas Rosene (1) Dylan Neel (5) Elisabeth Alicot (3) Felipe Pinho-Ribeiro (8) Francis Moore (3) Frank Austen (2) Gangjian Qin (2) Georgia Gunner (2) Glendon Wu (2) Himanish Basu (6) Isaac Chiu (72) Isaac Chiu (10) Jack Strominger (4) Jennifer Gibbs (3) Jinan Li (4) Jonathan Abraham (2) Juan-Manuel Leyva-Castillo (3) Jun Huh (2) Juraj Kabat (2) Kenneth Plante (2) Kimbria Blake (6) Lee Rubin (2) Leonard Zon (1) Liwen Deng (12) Meenakshi Rao (2) Melissa Musser (2) Meng Wu (2) Michael Carroll (7) Michel Enamorado (2) Ming Zhang (3) Na-Ryum Bin (2) Nader Ghasemlou (4) Nicolas Bouladoux (2) Nicola Verna (2) Nicole Lai (3) Nicole Lai (2) Nicole Yang (4) Ofer Mandelboim (2) Olena Kamenyeva (2) Ozge Erdogan (4) Pankaj Baral (7) Pan Yang (2) Patrick Burkett (4) Paula Montero Llopis (2) Pingchuan Ma (2) Raif Geha (2) Raja-Elie Abdulnour (3) Ralph Weissleder (1) Richard Lee (1) Samantha Choi (4) Samantha Riesenfeld (3) Scott Weaver (2) Sean O'Keeffe (1) Seungkyu Lee (3) Stephanie Shiers (3) Stephen Liberles (4) Swalpa Udit (2) Theodore Price (3) Thiago Cunha (2) Tiandi Yang (2) Tiphaine Voisin (9) Tom Maniatis (2) Valentina Lagomarsino (2) Verena Link (2) Vesna Brusic (2) Victoria Tong (2) Vijay Kuchroo (6) Waldiceu Verri (2) Warakorn Kulalert (2) Xi Chen (2) Yan Zhou (2) Yasmine Belkaid (2) Yiqing Yan (2) Search Within Results Search Within Results search ## 96 results Show filters filter\_alt Sort by Year of PublicationAlphabetical A-Z sort ## 96 results Download 96 citations download- [BibTeX](/node/1926886/export?format=bibtex) - [EndNote X3 XML](/node/1926886/export?format=endnote8) - [EndNote 7 XML](/node/1926886/export?format=endnote7) - [Endnote tagged](/node/1926886/export?format=tagged) - [Marc](/node/1926886/export?format=marc) - [PubMedId](/node/1926886/export?format=pubmed_id) - [RIS](/node/1926886/export?format=ris) ### 2025 Nicole Almanzar, Daping Yang, Jingya Xia, Swalpa Udit, Prabhu Joshi, Sandeep Adhikari, Daisy A Hoagland, Stephen T Yeung, Camille Khairallah, Tomas Huerta, Antonia Wallrapp, Benjamin D Umans, Nicole Sarden, Ozge Erdogan, Nadia Baalbaki, Jiawei Hou, Anna Beekmayer-Dhillon, Juhyun Lee, Kimberly A Meerschaert, Stephen D Liberles, Ruth A Franklin, Bryan G Yipp, Kamal M Khanna, Pankaj Baral, Adam L Haber, and Isaac M Chiu. 2025. “[Vagal TRPV1 Sensory Neurons Protect Against Influenza Virus Infection by Regulating Lung Myeloid Cell Dynamics.](/publication/vagal-trpv1-sensory-neurons-protect-against-influenza-virus-infection-regulating-lung)”. Science Immunology, 10, 110, Pp. eads6243. doi:10.1126/sciimmunol.ads6243 Nicole Almanzar, Daping Yang, Jingya Xia, Swalpa Udit, Prabhu Joshi, Sandeep Adhikari, Daisy A Hoagland, Stephen T Yeung, Camille Khairallah, Tomas Huerta, Antonia Wallrapp, Benjamin D Umans, Nicole Sarden, Ozge Erdogan, Nadia Baalbaki, Jiawei Hou, Anna Beekmayer-Dhillon, Juhyun Lee, Kimberly A Meerschaert, Stephen D Liberles, Ruth A Franklin, Bryan G Yipp, Kamal M Khanna, Pankaj Baral, Adam L Haber, and Isaac M Chiu. 2025. “[Vagal TRPV1 Sensory Neurons Protect Against Influenza Virus Infection by Regulating Lung Myeloid Cell Dynamics.](/publication/vagal-trpv1-sensory-neurons-protect-against-influenza-virus-infection-regulating-lung)”. Science Immunology, 10, 110, Pp. eads6243. doi:10.1126/sciimmunol.ads6243 - add\_circle do\_not\_disturb\_on Abstract - [ downloadScience Immunology Article](https://www.science.org/stoken/author-tokens/ST-2794/full) Influenza viruses are a major global cause of morbidity and mortality. Although vagal TRPV1 nociceptive sensory neurons are known to mediate defenses against harmful agents, including pathogens, their function in lung antiviral defenses remains unclear... - [ downloadScience Immunology Article](https://www.science.org/stoken/author-tokens/ST-2794/full) Georgia Gunner, Himanish Basu, Yueting Lu, Matthew Bergstresser, Liwei Sun, Dylan Neel, So Yoen Choi, and Isaac M Chiu. 2025. “[Gasdermin D Is Activated But Does Not Drive Neurodegeneration in SOD1 Model of ALS: Implications for Targeting Pyroptosis.](/publication/gasdermin-d-activated-does-not-drive-neurodegeneration-sod1-model-als-implications)”. Neurobiology of Disease, 214, Pp. 107048. doi:10.1016/j.nbd.2025.107048 Georgia Gunner, Himanish Basu, Yueting Lu, Matthew Bergstresser, Liwei Sun, Dylan Neel, So Yoen Choi, and Isaac M Chiu. 2025. “[Gasdermin D Is Activated But Does Not Drive Neurodegeneration in SOD1 Model of ALS: Implications for Targeting Pyroptosis.](/publication/gasdermin-d-activated-does-not-drive-neurodegeneration-sod1-model-als-implications)”. Neurobiology of Disease, 214, Pp. 107048. doi:10.1016/j.nbd.2025.107048 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-08/PDF_1.pdf) - [ downloadNeurobiology of Disease Article](https://www.sciencedirect.com/science/article/pii/S0969996125002645?via%3Dihub) Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive motor neuron loss, microgliosis, and neuroinflammation. While pyroptosis, an inflammatory form of programmed cell death, has been implicated in ALS, the... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-08/PDF_1.pdf) - [ downloadNeurobiology of Disease Article](https://www.sciencedirect.com/science/article/pii/S0969996125002645?via%3Dihub) Himanish Basu, Coco Holliday, and Isaac M. Chiu. 2025. “[Neuronal VPS13D Loss Drives Microglial Activation](/publication/neuronal-vps13d-loss-drives-microglial-activation)”. Nature Structural & Molecular Biology Himanish Basu, Coco Holliday, and Isaac M. Chiu. 2025. “[Neuronal VPS13D Loss Drives Microglial Activation](/publication/neuronal-vps13d-loss-drives-microglial-activation)”. Nature Structural & Molecular Biology - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_3.pdf) - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_3.pdf) Calvin Wong and Isaac M. Chiu. 2025. “[Neurotransmitter and Neuropeptide Regulation of Gut Immunity](/publication/neurotransmitter-and-neuropeptide-regulation-gut-immunity)”. Current Opinion in Neurobiology, 92:103036 Calvin Wong and Isaac M. Chiu. 2025. “[Neurotransmitter and Neuropeptide Regulation of Gut Immunity](/publication/neurotransmitter-and-neuropeptide-regulation-gut-immunity)”. Current Opinion in Neurobiology, 92:103036 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_4.pdf) - [ descriptionCurrent Opinion in Neurobiology Review](https://www.sciencedirect.com/science/article/pii/S0959438825000674?via%3Dihub) It is increasingly clear that the nervous system and immune system share a common molecular dialogue for intersystem communication. One of the key mechanisms of this communication is via neurotransmitters and neuropeptides. Diverse neuronal subtypes... - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_4.pdf) - [ descriptionCurrent Opinion in Neurobiology Review](https://www.sciencedirect.com/science/article/pii/S0959438825000674?via%3Dihub) Xiaoyi Fan, Wanyu Li, Jessica Oros, Jessica A Plante, Brooke M Mitchell, Jesse S Plung, Himanish Basu, Sivapratha Nagappan-Chettiar, Joshua M Boeckers, Laurentia Tjang V, Colin J Mann, Vesna Brusic, Tierra K Buck, Haley Varnum, Pan Yang, Linzy M Malcolm, So Yoen Choi, William M de Souza, Isaac M. Chiu, Hisashi Umemori, Scott C Weaver, Kenneth S Plante, and Jonathan Abraham. 2025. “[Molecular Basis for Shifted Receptor Recognition by an Encephalitic Arbovirus](/publication/molecular-basis-shifted-receptor-recognition-encephalitic-arbovirus)”. Cell, 188(11)2957-2973.e28, 11 Xiaoyi Fan, Wanyu Li, Jessica Oros, Jessica A Plante, Brooke M Mitchell, Jesse S Plung, Himanish Basu, Sivapratha Nagappan-Chettiar, Joshua M Boeckers, Laurentia Tjang V, Colin J Mann, Vesna Brusic, Tierra K Buck, Haley Varnum, Pan Yang, Linzy M Malcolm, So Yoen Choi, William M de Souza, Isaac M. Chiu, Hisashi Umemori, Scott C Weaver, Kenneth S Plante, and Jonathan Abraham. 2025. “[Molecular Basis for Shifted Receptor Recognition by an Encephalitic Arbovirus](/publication/molecular-basis-shifted-receptor-recognition-encephalitic-arbovirus)”. Cell, 188(11)2957-2973.e28, 11 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_7.pdf) Western equine encephalitis virus (WEEV) is an arbovirus that historically caused large outbreaks of encephalitis throughout the Americas. WEEV binds protocadherin 10 (PCDH10) as a receptor, and highly virulent ancestral WEEV strains also bind low-density... - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_7.pdf) Hung Chan, Fengwu Li, Tatsuya Dokoshi, Kellen J. Cavagnero, Qing Li, Yang Chen, Carlos Aguilera, Teruaki Nakatsuji, Edward Liu, Aaryan Indra, Daping Yang, Ottaviani Valentina, Tomofumi Numata, Brittany Crown, Henry Li, Kevin J. Williams, Isaac M. Chiu, Steven J. Bensinger, WanJun Chen, and Richard L. Gallo. 2025. “[Psychological Stress Increases Skin Infection through the Action of TGFβ to Suppress Immune-Acting Fibroblasts](/publication/psychological-stress-increases-skin-infection-through-action-tgfb-suppress-immune)”. Sci Immunol , 10, 106 Hung Chan, Fengwu Li, Tatsuya Dokoshi, Kellen J. Cavagnero, Qing Li, Yang Chen, Carlos Aguilera, Teruaki Nakatsuji, Edward Liu, Aaryan Indra, Daping Yang, Ottaviani Valentina, Tomofumi Numata, Brittany Crown, Henry Li, Kevin J. Williams, Isaac M. Chiu, Steven J. Bensinger, WanJun Chen, and Richard L. Gallo. 2025. “[Psychological Stress Increases Skin Infection through the Action of TGFβ to Suppress Immune-Acting Fibroblasts](/publication/psychological-stress-increases-skin-infection-through-action-tgfb-suppress-immune)”. Sci Immunol , 10, 106 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-07/PDF_2.pdf) Infections after psychological stress are a major health care problem. Single-cell transcriptomics and lipidomic profiling in a mouse model of stress show that dermal fibroblasts undergoing adipogenesis have defective responses to *Staphylococcus aureus* sk... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-07/PDF_2.pdf) Elizabeth N Chung, Jinsu Lee, Carolina M Polonio, Joshua Choi, Camilo Faust Akl, Michael Kilian, Wiebke M Weiß, Georgia Gunner, Mingyu Ye, Tae Hyun Heo, Sienna S Drake, Liu Yang, Catarina R G L d’Eca, Joon-Hyuk Lee, Liwen Deng, Daniel Farrenkopf, Anton M. Schüle, Hong-Gyun Lee, Oreoluwa Afolabi, Sharmin Ghaznavi, Stelios M. Smirnakis, Isaac M. Chiu, Vijay K. Kuchroo, Francisco J. Quintana, and Michael A. Wheeler. 2025. “[Psychedelic Control of Neuroimmune Interactions Governing Fear](/publication/psychedelic-control-neuroimmune-interactions-governing-fear)”. Nature, 641, 1276–1286 Elizabeth N Chung, Jinsu Lee, Carolina M Polonio, Joshua Choi, Camilo Faust Akl, Michael Kilian, Wiebke M Weiß, Georgia Gunner, Mingyu Ye, Tae Hyun Heo, Sienna S Drake, Liu Yang, Catarina R G L d’Eca, Joon-Hyuk Lee, Liwen Deng, Daniel Farrenkopf, Anton M. Schüle, Hong-Gyun Lee, Oreoluwa Afolabi, Sharmin Ghaznavi, Stelios M. Smirnakis, Isaac M. Chiu, Vijay K. Kuchroo, Francisco J. Quintana, and Michael A. Wheeler. 2025. “[Psychedelic Control of Neuroimmune Interactions Governing Fear](/publication/psychedelic-control-neuroimmune-interactions-governing-fear)”. Nature, 641, 1276–1286 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_5.pdf) Neuroimmune interactions-signals transmitted between immune and brain cells-regulate many aspects of tissue physiology1, including responses to psychological stress2-5, which can predispose individuals to develop neuropsychiatric diseases6-9. Still, the... - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_5.pdf) Miguel Marin-Rodero, Elisa Cintado, Alec J. Walker, Teshika Jayewickreme, Felipe Pinho-Ribeiro, Quentin Richardson, Ruaidhrí Jackson, Isaac M. Chiu, Christophe Benoist, Beth Stevens, José Luís Trejo, and Diane Mathis. 2025. “[The Meninges Host a Distinct Compartment of Regulatory T Cells That Preserves Brain Homeostasis](/publication/meninges-host-distinct-compartment-regulatory-t-cells-preserves-brain-homeostasis)”. Sci Immunol, 10, 104 Miguel Marin-Rodero, Elisa Cintado, Alec J. Walker, Teshika Jayewickreme, Felipe Pinho-Ribeiro, Quentin Richardson, Ruaidhrí Jackson, Isaac M. Chiu, Christophe Benoist, Beth Stevens, José Luís Trejo, and Diane Mathis. 2025. “[The Meninges Host a Distinct Compartment of Regulatory T Cells That Preserves Brain Homeostasis](/publication/meninges-host-distinct-compartment-regulatory-t-cells-preserves-brain-homeostasis)”. Sci Immunol, 10, 104 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_0.pdf) Our understanding of the meningeal immune system has recently burgeoned, particularly regarding how innate and adaptive effector cells are mobilized to meet brain challenges. However, information on how meningeal immunocytes guard brain homeostasis in... - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_0.pdf) Ozge Erdogan, Xiao-Qian Hu, and Isaac M. Chiu. 2025. “[Sensory Neurons on Guard: Roles in Pathogen Defense and Host Immunity](/publication/sensory-neurons-guard-roles-pathogen-defense-and-host-immunity)”. Current Opinion in Immunology , 93, 102541 Ozge Erdogan, Xiao-Qian Hu, and Isaac M. Chiu. 2025. “[Sensory Neurons on Guard: Roles in Pathogen Defense and Host Immunity](/publication/sensory-neurons-guard-roles-pathogen-defense-and-host-immunity)”. Current Opinion in Immunology , 93, 102541 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_1.pdf) - [ descriptionCurrent Opinion in Immunology Review](https://www.sciencedirect.com/science/article/pii/S0952791525000172?via%3Dihub) The nervous system, like the immune system, constantly interfaces with the environment, encountering threats, including pathogens. Recent discoveries reveal an emerging role for sensory neurons in host defense and immunity. Sensory neurons detect... - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF_1.pdf) - [ descriptionCurrent Opinion in Immunology Review](https://www.sciencedirect.com/science/article/pii/S0952791525000172?via%3Dihub) ### 2024 Kimberly A Meerschaert and Isaac M Chiu. 2024. “[The Gut-Brain Axis and Pain Signalling Mechanisms in the Gastrointestinal Tract](/publication/gut-brain-axis-and-pain-signalling-mechanisms-gastrointestinal-tract)”. Nature Reviews 22, 206–221 Kimberly A Meerschaert and Isaac M Chiu. 2024. “[The Gut-Brain Axis and Pain Signalling Mechanisms in the Gastrointestinal Tract](/publication/gut-brain-axis-and-pain-signalling-mechanisms-gastrointestinal-tract)”. Nature Reviews 22, 206–221 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-04/the_gut-brain_axis_and_pain_signalling_mechanisms_in_the_gastrointestinal_tract_0.pdf) - [ descriptionNature Reviews Gastro and Hepatology](https://www.nature.com/articles/s41575-024-01017-9) Visceral pain is a major clinical problem and one of the most common reasons patients with gastrointestinal disorders seek medical help. Peripheral sensory neurons that innervate the gut can detect noxious stimuli and send signals to the central nervous... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-04/the_gut-brain_axis_and_pain_signalling_mechanisms_in_the_gastrointestinal_tract_0.pdf) - [ descriptionNature Reviews Gastro and Hepatology](https://www.nature.com/articles/s41575-024-01017-9) Isaac M Chiu and Caroline L Sokol. 2024. “[Neuroimmune Recognition of Allergens](/publication/neuroimmune-recognition-allergens)”. Current Opinion in Immunology 90, 102458 Isaac M Chiu and Caroline L Sokol. 2024. “[Neuroimmune Recognition of Allergens](/publication/neuroimmune-recognition-allergens)”. Current Opinion in Immunology 90, 102458 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-04/neuroimmune_recognition_of_allergens__0.pdf) - [Current Opinion in Immunology Review](https://www.sciencedirect.com/science/article/pii/S0952791524000487?via%3Dihub) Interactions between the nervous system and the immune system play crucial roles in initiating and directing the type 2 immune response. Sensory neurons can initiate innate and adaptive type 2 immunity through their ability to detect allergens and promote... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum8911/files/2025-04/neuroimmune_recognition_of_allergens__0.pdf) - [Current Opinion in Immunology Review](https://www.sciencedirect.com/science/article/pii/S0952791524000487?via%3Dihub) Yu Hou, Linyu Sun, Martin W. LaFleur, Linglin Huang, Conner Lambden, Pratiksha I. Thakore, Kathryn Geiger-Schuller, Kimitoshi Kimura, Longjun Yan, Yue Zhang, Ruihan Tang, Jingwen Shi, Rocky Barilla, Liwen Deng, Ayshwarya Subramanian, Antonia Wallrapp, Hee Sun Choi, Yoon-Chul Kye, Orr Ashenberg, Geoffrey Schiebinger, John G. Doench, Isaac M. Chiu, Aviv Regev, Arlene H. Sharpe, and Vijay K. Kuchroo. 2024. “[Neuropeptide Signalling Orchestrates T Cell Differentiation](/publication/neuropeptide-signalling-orchestrates-t-cell-differentiation)”. Nature, 635, 444–452 Yu Hou, Linyu Sun, Martin W. LaFleur, Linglin Huang, Conner Lambden, Pratiksha I. Thakore, Kathryn Geiger-Schuller, Kimitoshi Kimura, Longjun Yan, Yue Zhang, Ruihan Tang, Jingwen Shi, Rocky Barilla, Liwen Deng, Ayshwarya Subramanian, Antonia Wallrapp, Hee Sun Choi, Yoon-Chul Kye, Orr Ashenberg, Geoffrey Schiebinger, John G. Doench, Isaac M. Chiu, Aviv Regev, Arlene H. Sharpe, and Vijay K. Kuchroo. 2024. “[Neuropeptide Signalling Orchestrates T Cell Differentiation](/publication/neuropeptide-signalling-orchestrates-t-cell-differentiation)”. Nature, 635, 444–452 - add\_circle do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF.pdf) The balance between T helper type 1 (TH1) cells and other TH cells is critical for antiviral and anti-tumour responses1-3, but how this balance is achieved remains poorly understood. Here we dissected the dynamic regulation of TH1 cell differentiation... - [ picture\_as\_pdfPDF.pdf](/sites/g/files/omnuum8911/files/2025-07/PDF.pdf) - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [3](?page=2 "Go to page 3") - [ Last page 8 ](?page=7 "Go to last page") - [ Next page chevron\_right ](?page=1 "Go to next page")